Review on Meridia

Whenever you hear about Meridia in the USA, it is actually the same thing as Reductil but in Europe, being an orally administered agent for the treatment of obesity, approved by the FDA sometime in November 1997. It is a centrally acting stimulant chemically related to amphetamines, so it is classified as a Schedule IV controlled substance in the USA.

The main component behind Meridia is Sibutramine, being a neurotransmitter reuptake inhibitor. It acts by helping enhance satiety by inhibiting the reuptake of serotonin by 53%, norepinephrine by 54% and dopamine by 16% in the brain. So in one, it strongly influences the appetite without having any antidepressant properties.

When declaring war to unwanted fat with the help of Meridia, it is recommendable to ask a health care specialist first, or do it under the surveillance of your physician. When clinically tested, individuals taking Meridia have described the following side effects: dry mouth, paradoxically increased appetite, nausea, strange taste in the mouth, anorgasmia and delayed ejaculation, upset stomach, constipation, trouble sleeping, dizziness, drowsiness, menstrual cramps/pain, headache, flushing, or joint/muscle pain. Its main component, the Sibutramine also increased blood pressure and pulse in some patients.

A revealing fact is that no case of pulmonary hypertension has been noted, although related compounds such as Fen-Phen is brought in connection with this rare but clinically significant problem.

Please note that due to its effects Sibutramine is contraindicated in: psychiatric conditions as bulimia nervosa, anorexia nervosa, serious depression or preexisting mania, patients with a history of or a predisposition to drug or alcohol abuse, existing pulmonary hypertension, overactive thyroid gland, seizure disorders and pregnant or lactating women should definitely not use the pill.